Map1b Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comMap1b Polyclonal Antibody for Mouse(Mus musculus)

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Map1b (Gene name),

Microtubule-associated protein 1B (Protein name ), MAP1B_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map1b(Mtap1b;Mtap5);

Protein name:

Microtubule-associated protein 1B(MAP-1B);

Alternative:

MAP1.2;MAP1(X);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. LC1 interacts with the amino-terminal region of MAP1B. Interacts with ANP32A and TIAM2. Interacts (via C-terminus) with GAN (via Kelch domains).

Function:

The function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.

Subcellular Location:

Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

2464

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VMQDESFPAC | KIEL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.4173

Pfam:

PF00414

KEGG:

mmu:17755

String:

P14873

Uniprot:

P14873

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ELISA Kit for Mouse MAP-1B

Cat.:

E9938h

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96T

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ELISA Kit for Mouse MAP-1B

Cat.:

E9938m

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96T

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ELISA Kit for Mouse MAP-1B

Cat.:

E9938r

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96T

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CLIA Kit for Mouse MAP-1B

Cat.:

U9938m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MAP-1B

Cat.:

U9938h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MAP-1B

Cat.:

U9938r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse MAP-1B

Cat.:

P9938Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MAP-1B

Cat.:

P9938Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MAP-1B

Cat.:

P9938Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse MAP-1B

Protein for Mouse MAP-1B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau."
Noble M. , Lewis S.A. , Cowan N.J.
J. Cell Biol.109:3367-3376(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DOMAIN
strain: Swiss Webster.
tissue: Brain.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin."
Ding J. , Liu J.-J. , Kowal A.S. , Nardine T. , Bhattacharya P. , Lee A. , Yang Y.
J. Cell Biol.158:427-433(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GAN
4.

"Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis."
Opal P. , Garcia J.J. , Propst F. , Matilla A. , Orr H.T. , Zoghbi H.Y.
J. Biol. Chem.278:34691-34699(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ANP32A
5.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1260; SER-1391 AND SER-1395;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.
6.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-541; SER-544; SER-561; SER-989; SER-1013; SER-1307; SER-1438; SER-1775 AND SER-1911;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
7.

"Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation."
Takefuji M. , Mori K. , Morita Y. , Arimura N. , Nishimura T. , Nakayama M. , Hoshino M. , Iwamatsu A. , Murohara T. , Kaibuchi K. , Amano M.
Biochem. Biophys. Res. Commun.355:788-794(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TIAM2
8.

"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain cortex.
9.

"S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction."
Stroissnigg H. , Trancikova A. , Descovich L. , Fuhrmann J. , Kutschera W. , Kostan J. , Meixner A. , Nothias F. , Propst F.
Nat. Cell Biol.9:1035-1045(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION AT CYS-2460
10.

"Microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination."
Utreras E. , Jimenez-Mateos E.M. , Contreras-Vallejos E. , Tortosa E. , Perez M. , Rojas S. , Saragoni L. , Maccioni R.B. , Avila J. , Gonzalez-Billault C.
Dev. Neurosci.30:200-210(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF ALPHA-TUBULIN TYROSINATION;INTERACTION WITH TTL
11.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-614; SER-1438; SER-1497 AND SER-1775;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
12.

"Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation."
Tortosa E. , Montenegro-Venegas C. , Benoist M. , Hartel S. , Gonzalez-Billault C. , Esteban J.A. , Avila J.
J. Biol. Chem.286:40638-40648(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION

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